Process of Progression of Coronary Artery Lesions From Mild or Moderate Stenosis to Moderate or Severe Stenosis

Process of progression of coronary artery lesions from mild or moderate stenosis to moderate or severe stenosis: A study based on four serial coronary arteriograms per year.

BACKGROUND The process of progression in coronary artery disease is unknown. METHODS AND RESULTS The subjects were 36 patients with 36 objective vessels with clinically significant progression of coronary artery disease (>/=15% per year) in whom 4 serial coronary arteriograms (CAGs) were performed at intervals of approximately 4 months in a 1-year period. The degree of progression of percent ...

Should patients with asymptomatic mild or moderate aortic stenosis undergoing coronary artery bypass surgery also have valve replacement for their aortic stenosis?

Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis.

H ENRY J.M. B ARNETT , M.D., D. W AYNE T AYLOR , M.A., M ICHAEL E LIASZIW , P H .D., A LLAN J. F OX , M.D., G ARY G. F ERGUSON , M.D., R. B RIAN H AYNES , M.D., R ICHARD N. R ANKIN , M.D., G. P ATRICK C LAGETT , M.D., V LADIMIR C. H ACHINSKI , M.D., D AVID L. S ACKETT , M.D., K EVIN E. T HORPE , M.M ATH ., AND H EATHER E. M ELDRUM , B.A., FOR THE N ORTH A MERICAN S YMPTOMATIC C AROTID E NDARTER...

Pulmonary atresia or severe stenosis and coronary artery-to-pulmonary artery fistula.

Five patients have had the common features of pulmonary atresia or severe stenosis associated with a septal defect and a coronary artery-to-pulmonary artery (CA-PA) fistula. Four had pulmonary valvular atresia, and one had severe pulmonary stenosis. In all five, the CA-PA fistula contributed the principal component of the pulmonary blood flow. Cyanosis, continuous murmur, right ventricular hype...

Should coronary artery bypass graft surgery patients with mild or moderate aortic stenosis undergo concomitant aortic valve replacement? A decision analysis approach to the surgical dilemma.

OBJECTIVES This study utilizes Markov decision analysis to assess the relative benefits of prophylactic aortic valve replacement (AVR) at the time of coronary artery bypass graft surgery (CABG). Multiple sensitivity analyses were also performed to determine the variables that most profoundly affect outcome. BACKGROUND The decision to perform CABG or concomitant CABG and AVR (CABG/AVR) in asym...